In Human, the Warburg micro syndrome (WARBM) is a genetic heterogeneous disease characterized by microcephaly, intellectual disability, brain-, ocular-, and endocrine anomalies. The group of Prof. Leeb from the University of Bern identified a mutation in Huskies, specifically in those bred for sledging, which apparently causes the same symptoms: microphtalmia and progressive neurological disorders (i.e. ataxia). Because of the clinical symptoms, diseased dogs are euthanized within a few months. In cooperation with Prof. Leeb, we have developed a routine test, helping to avoid the birth of dogs with this fatal disease.